全文获取类型
收费全文 | 13969篇 |
免费 | 624篇 |
国内免费 | 70篇 |
专业分类
耳鼻咽喉 | 37篇 |
儿科学 | 447篇 |
妇产科学 | 4479篇 |
基础医学 | 1399篇 |
口腔科学 | 80篇 |
临床医学 | 1005篇 |
内科学 | 940篇 |
皮肤病学 | 103篇 |
神经病学 | 336篇 |
特种医学 | 362篇 |
外国民族医学 | 10篇 |
外科学 | 1120篇 |
综合类 | 1118篇 |
预防医学 | 1110篇 |
眼科学 | 29篇 |
药学 | 638篇 |
30篇 | |
中国医学 | 75篇 |
肿瘤学 | 1345篇 |
出版年
2023年 | 580篇 |
2022年 | 786篇 |
2021年 | 972篇 |
2020年 | 910篇 |
2019年 | 622篇 |
2018年 | 433篇 |
2017年 | 720篇 |
2016年 | 633篇 |
2015年 | 570篇 |
2014年 | 1258篇 |
2013年 | 858篇 |
2012年 | 746篇 |
2011年 | 594篇 |
2010年 | 749篇 |
2009年 | 738篇 |
2008年 | 275篇 |
2007年 | 402篇 |
2006年 | 328篇 |
2005年 | 257篇 |
2004年 | 171篇 |
2003年 | 197篇 |
2002年 | 229篇 |
2001年 | 200篇 |
2000年 | 159篇 |
1999年 | 175篇 |
1998年 | 140篇 |
1997年 | 129篇 |
1996年 | 105篇 |
1995年 | 34篇 |
1994年 | 20篇 |
1993年 | 32篇 |
1992年 | 60篇 |
1991年 | 59篇 |
1990年 | 46篇 |
1989年 | 45篇 |
1988年 | 37篇 |
1987年 | 23篇 |
1985年 | 40篇 |
1984年 | 46篇 |
1983年 | 27篇 |
1982年 | 27篇 |
1981年 | 18篇 |
1980年 | 22篇 |
1979年 | 18篇 |
1978年 | 19篇 |
1977年 | 20篇 |
1976年 | 16篇 |
1975年 | 11篇 |
1974年 | 11篇 |
1973年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 218 毫秒
1.
《International journal of oral and maxillofacial surgery》2022,51(3):332-337
The purpose of this study was to investigate the association between habitual snoring (HS), middle ear disease (MED), and speech problems in children with cleft palate. This cross-sectional study included children aged 2.0–7.9 years with non-syndromic cleft palate anomalies. Parents completed the Pediatric Sleep Questionnaire and a questionnaire about MED. Audiograms and speech assessment were also conducted. Ninety-five children were enrolled; 15.2% of families reported HS, 97.6% MED, and 17.1% speech problems. HS (37.5% vs 10.3%, P = 0.007) and early episodes of MED (92.3% vs 58.2%, P = 0.021) were more likely to be reported for children with isolated cleft palate when compared to those with cleft lip and palate. Children with cleft lip and palate had a higher frequency of MED with effusion compared to those with Robin sequence (86.4% vs 57.1%, P = 0.049). The odds ratio for HS in children with ≥1 episode of MED in the last year was 7.37 (95% confidence interval 1.55–35.15, P = 0.012). There was a trend for children with speech problems reported by parents to have HS (30.8% vs 11.5%, P= 0.076). Anatomical factors play a role in the frequency of upper airway symptoms in children with cleft palate. A recent history of at least one episode of MED was associated with an increased frequency of HS. 相似文献
2.
3.
《Journal of manipulative and physiological therapeutics》2022,45(3):227-234
ObjectiveThe purpose of this study was to determine the accuracy and intrarater reliability of a palpatory protocol based on a combination of 3 palpatory methods to identify both the C7 spinous process (C7 SP) and the factors that affect the errors and inaccuracy of palpation.MethodsTwenty-five women between the ages of 18 and 60 years were submitted to a palpation protocol of the C7 SP, and a radiopaque marker was fixed on the skin at the possible location of the vertebrae. A radiograph and a photograph of the cervical spine were obtained in the same posture by a first rater. A second rater performed the same palpation protocol and took a second photograph. The accuracy and measurement error of the palpation protocol of C7 SP were assessed through radiographic images. The inter-rater reliability was estimated by the interclass correlation coefficient and assessed using photographs of each rater. The Pearson's correlation coefficients (r), the Fisher exact test, and the χ2 test were used to identify the factors associated with the error and inaccuracy of palpation.ResultsAccuracy of the C7 palpation was 76% with excellent reliability (interclass correlation coefficient = 0.99). There was a moderate correlation between weight and the measurement of palpation error (r = –0.6; P = .003). One hundred percent of inaccuracy palpation was related to the increased soft-tissue thickness (P = .005) in the cervical region.ConclusionThe palpation protocol described in this study was accurate and presented excellent reliability in identifying the C7 SP. Increased weight and dorsocervical fat pad were associated to error and palpation inaccuracy, respectively. 相似文献
4.
Although methadone is effective in the management of acute pain, the complexity of its absorption-distribution-metabolism-excretion profile limits its use as an opioid of choice for perioperative analgesia. Because deuteration is known to improve the pharmacokinetic, pharmacodynamic and toxicological properties of some drugs, here we characterized the single dose pharmacokinetic properties and post-operative analgesic efficacy of d9-methadone.The pharmacokinetic profiles of d9-methadone and methadone administered intravenously to CD-1 male mice revealed that deuteration leads to a 5.7- and 4.4-fold increase in the area under the time-concentration curve and maximum concentration in plasma, respectively, as well as reduction in clearance (0.9 ± 0.3 L/h/kg vs 4.7 ± 0.8 L/h/kg). The lower brain-to-plasma ratio of d9-methadone compared to that of methadone (0.35 ± 0.12 vs 2.05 ± 0.62) suggested that deuteration decreases the transfer of the drug across the blood-brain barrier. The estimated LD50 value for a single intravenous dose of d9-methadone was 2.1-fold higher than that for methadone. Moreover, d9-methadone outperformed methadone in the efficacy against postoperative pain by primarily activating peripheral opioid receptors. Collectively, these data suggest that the replacement of three hydrogen atoms in three methyl groups of methadone altered its pharmacokinetic properties, improved safety, and enhanced its analgesic efficacy. 相似文献
5.
6.
《Seminars in perinatology》2022,46(3):151524
Addressing bias and disparities in counseling and care requires that we contend with dehumanizing attitudes, stereotypes, and beliefs that our society and profession holds towards people of color, broadly, and Black birthing people in particular. It also necessitates an accounting of the historically informed, racist ideologies that shape present-day implicit biases. These biases operate in a distinctly complex and damaging manner in the context of end-of-life care, which centers around questions related to human pain, suffering, and value. Therefore, this paper aims to trace biases and disparities that operate in periviable care, where end-of-life decisions are made at the very beginning of life. We start from a historical context to situate racist ideologies into present day stereotypes and tropes that dehumanize and disadvantage Black birthing people and Black neonates in perinatal care. Here, we review the literature, address historical incidents and consider their impact on our ability to deliver patient-centered periviable care. 相似文献
7.
8.
9.
10.
《The American journal of emergency medicine》2020,38(1):163.e3-163.e5
Impacted esophageal foreign bodies typically first present to the emergency department, with coins being most common in children and food boluses most common in adults. Controversy exists regarding the best treatment options in these cases. We report two cases, one pediatric and one adult, where the use of a novel substitute Hurst dilator constructed of materials regularly found in all EDs was successfully used to treat impacted esophageal foreign bodies. 相似文献